Rimonabant hydrochloride
Synonym(s):5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide hydrochloride;SR141716;SR-141716;SR141716A;SR-141716A
- CAS NO.：158681-13-1
- Empirical Formula: C22H21Cl3N4O.ClH
- Molecular Weight: 500.25
- MDL number: MFCD00934884
- EINECS: 233-720-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Rimonabant hydrochloride?
Chemical properties
White to Off-White Crystalline Solid
The Uses of Rimonabant hydrochloride
Rimonabant hydrochloride has been used as an antagonist of cannabinoid 1 (CB1) receptor:
- to study its effects on protein synthesis in C2C12 myotubes
- to analyze its effects on human astroglia
- in combination with methanandamide (mAEA) to study its effects on murine gastric vagal afferent mechanosensitivity
The Uses of Rimonabant hydrochloride
The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists
The Uses of Rimonabant hydrochloride
A brain cannabinoid receptor (CB1) antagonist. Antiobesity agent.
What are the applications of Application
Rimonabant Hydrochloride is a CB1 (cannabinoid receptor 1) antagonist
Hazard
A poison.
Biochem/physiol Actions
Rimonabant acts as a mycobacterial membrane protein large 3 (MMPL3) inhibitor. Rimonabant hydrochloride exhibits therapeutic activity against weight reduction and smoking cessation.
Storage
Desiccate at RT
Properties of Rimonabant hydrochloride
| Melting point: | 230-240°C |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| CAS DataBase Reference | 158681-13-1(CAS DataBase Reference) |
Safety information for Rimonabant hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Rimonabant hydrochloride
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