RIBONUCLEASE T1
Synonym(s):Guanyloribonuclease;Ribonucleate 3′-guanylo-oligonucleotidohydrolase
- CAS NO.：9026-12-4
- Molecular Weight: 0
- MDL number: MFCD00132191
- EINECS: 232-809-1
- Update Date: 2026-01-13 11:18:48
What is RIBONUCLEASE T1?
The Uses of RIBONUCLEASE T1
Ribonuclease T1 (RNase T1) from Aspergillus oryzae is used to digest denatured RNA prior to sequencing and is used for protein folding studies .
Biochem/physiol Actions
Ribonuclease T1 (RNase T1) from Aspergillus oryzae is an endoribonuclease that hydrolyzes after G residues. Cleavage occurs between the 3′-phosphate group of a guanidine ribonucleotide and 5′-hydroxyl of the adjacent nucleotide. The initial product is a 2′:3′ cyclic phosphate nucleoside that is hydrolyzed to the corresponding 3′-nucleoside phosphate. It differs from Pancreatic RNase in that it attacks the guanine sites specifically to yield 3′-GMP and oligonucleotides with a 3′-GMP terminal group.
Properties of RIBONUCLEASE T1
| storage temp. | 2-8°C |
| form | ammonium sulfate suspension |
| color | Colorless to light yellow |
Safety information for RIBONUCLEASE T1
Computed Descriptors for RIBONUCLEASE T1
New Products
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