Rh family, C glycoprotein

The Uses of Rh family, C glycoprotein

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

General Description

PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 γ) belongs to the phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) family. It is expressed at high levels in the brain. PIP4K2C is located on human chromosome 12q13.3.

Biochem/physiol Actions

The phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) modulates the levels of their substrate, PI5P. It participates in the metabolic control, growth control, and several stress responses. Absence of PIP4K2C leads to hyperactivation of the immune system.Type 2 phosphatidylinositol-5-phosphate 4-kinase (PI5P4K) helps in the conversion of phosphatidylinositol-5-phosphate to phosphatidylinositol-4,5-bisphosphate.