RESERPININE (Raubasinine)

Description

A constituent of Rauwolfia serpentina, the base also occurs in Vinca major and forms light yellow plates when crystallized from aqueous Me2CO. It has specific rotations of [α]²²_D - 95° (pyridine) and [α]²⁰_D - 131° (c 1.18, CHCl 3).1t yields crystalline salts and derivatives, e.g. the hydrochloride, m.p. 244-6°C (dec.); perchlorate, m.p. 254.5°C; nitrate, m.p. 271-3°C and the methiodide, m.p. 240° C (dec.). For the other alkaloid originally given this name see Rescinnamine.

References

Janot, LeMen., Compt. rend., 238,2550 (1954)
Schlittler, Saner, Miiller.,Experientia, 10,133 (1954)
Neuss, Boaz, Forbes.,J. Amer. Chem. Soc., 76,2463 (1954)
Shamma, Richey., ibid, 85,2507 (1963)