RCS-4 M10 metabolite

CAS NO.：1952336-77-4
Empirical Formula: C20H21NO3
Molecular Weight: 323.39
Update Date: 2023-05-04 17:34:35

What is RCS-4 M10 metabolite?

Description

RCS-4 is a synthetic cannabinoid which has been detected in herbal mixtures.¹ RCS-4 M10 metabolite is a major urinary metabolite of RCS-4, characterized by O-demethylation/monohydroxylation of the N-pentyl chain.² Its metabolism has been derived using GC-MS analysis.² This metabolite is potentially useful as a metabolic marker for the identification of RCS-4 ingestion and is therefore intended for research and forensic purposes.

Definition

ChEBI: Methanone, [1-(5-hydroxypentyl)-1h-indol-3-yl](4-hydroxyphenyl)- is a N-acylindole.

References

1. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).
2. Kavanagh, P., Grigoryev, A., Melnik, A., et al. The identification of the urinary metabolites of 3-(4-methoxybenzoyl)-1-pentylindole (RCS-4), a novel cannabimimetic, by gas chromatography-mass spectrometry J. Anal. Toxicol. 36,303-311(2012).

Properties of RCS-4 M10 metabolite

Boiling point:	565.9±40.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
solubility	DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
form	A crystalline solid
pka	8.04±0.15(Predicted)

Safety information for RCS-4 M10 metabolite

Computed Descriptors for RCS-4 M10 metabolite

New Products

Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2-Bromo-5-hydroxybenzoic acid. 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 4-Fluorophenylglycine 1-N-Boc-3-(aminoethyl)azetidine Dimedone 1-Boc-3-(cyanomethyl)azetidine N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile 5-Amino-2-Hydroxypyridine 2-Amino-5-Iodopyridine 2-BROMOACETYL BROMIDE-D2 METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3 6-Chloro-pyrimidine-2,4-diamine 3-Oxide 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochloride