RCS-4 M10 metabolite

CAS NO.：1952336-77-4
Empirical Formula: C20H21NO3
Molecular Weight: 323.39
Update Date: 2023-05-04 17:34:35

What is RCS-4 M10 metabolite?

Description

RCS-4 is a synthetic cannabinoid which has been detected in herbal mixtures.¹ RCS-4 M10 metabolite is a major urinary metabolite of RCS-4, characterized by O-demethylation/monohydroxylation of the N-pentyl chain.² Its metabolism has been derived using GC-MS analysis.² This metabolite is potentially useful as a metabolic marker for the identification of RCS-4 ingestion and is therefore intended for research and forensic purposes.

Definition

ChEBI: Methanone, [1-(5-hydroxypentyl)-1h-indol-3-yl](4-hydroxyphenyl)- is a N-acylindole.

References

1. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3),109-115(2011).
2. Kavanagh, P., Grigoryev, A., Melnik, A., et al. The identification of the urinary metabolites of 3-(4-methoxybenzoyl)-1-pentylindole (RCS-4), a novel cannabimimetic, by gas chromatography-mass spectrometry J. Anal. Toxicol. 36,303-311(2012).

Properties of RCS-4 M10 metabolite

Boiling point:	565.9±40.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
solubility	DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml
form	A crystalline solid
pka	8.04±0.15(Predicted)

Safety information for RCS-4 M10 metabolite

Computed Descriptors for RCS-4 M10 metabolite

New Products

3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine