RAC 8-HYDROXY EFAVIRENZ
- CAS NO.：205754-33-2
- Empirical Formula: C14H9ClF3NO3
- Molecular Weight: 331.67
- MDL number: MFCD09840726
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is RAC 8-HYDROXY EFAVIRENZ?
Description
8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.
Chemical properties
Off-White Solid
The Uses of RAC 8-HYDROXY EFAVIRENZ
A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor
The Uses of RAC 8-HYDROXY EFAVIRENZ
8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor.
Properties of RAC 8-HYDROXY EFAVIRENZ
| Melting point: | 144-154°C |
| Boiling point: | 373.6±42.0 °C(Predicted) |
| Density | 1?+-.0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Acetonitrile: soluble; DMSO: soluble; Methanol: soluble |
| form | A solid |
| pka | 7.18±0.40(Predicted) |
| color | White to off-white |
Safety information for RAC 8-HYDROXY EFAVIRENZ
Computed Descriptors for RAC 8-HYDROXY EFAVIRENZ
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
1122-58-3 99%View Details
1122-58-3 -
5-Methoxy-2-Mercapto Benzimidazole 99%View Details
37052-78-1 -
15128-52-6 99%View Details
15128-52-6 -
3,6-Dichloropyridazine 99%View Details
141-30-0 -
2-Chlorotrityl Chloride 99%View Details
42074-68-0 -
5-Bromo-2-chlorobenzoic acid 21739-92-4 99%View Details
21739-92-4 -
106-40-1 99%View Details
106-40-1 -
15128-52-6 1,2,3,9-Tetrahydro-4(H)-carbazol-4-one 99%View Details
15128-52-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.