R(+)-Verapamil monohydrochloride hydrate
- CAS NO.：38176-02-2
- Empirical Formula: C27H41ClN2O5
- Molecular Weight: 509.07784
- Update Date: 2023-05-04 17:34:38
What is R(+)-Verapamil monohydrochloride hydrate?
Definition
ChEBI: Dexverapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of dexverapamil and hydrogen chloride. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil hydrochloride exhibits lower calcium antagonistic activity and toxicity than racemic verapamil hydrochloride. It has a role as an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor. It contains a dexverapamil(1+). It is an enantiomer of a (S)-verapamil hydrochloride.
Properties of R(+)-Verapamil monohydrochloride hydrate
| storage temp. | desiccated |
Safety information for R(+)-Verapamil monohydrochloride hydrate
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for R(+)-Verapamil monohydrochloride hydrate
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