(R)-N-Fmoc-2-(7'-octenyl) alanine
Synonym(s):(R)-N-Fmoc-α-(7-Octenyl)alanine;Fmoc-(R)-2-(7-octenyl)alanine;Fmoc-(R)-2-amino-2-methyl-dec-6-enoic acid
- CAS NO.：945212-26-0
- Empirical Formula: C26H31NO4
- Molecular Weight: 421.53
- MDL number: MFCD12925761
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:51
What is (R)-N-Fmoc-2-(7'-octenyl) alanine?
The Uses of (R)-N-Fmoc-2-(7'-octenyl) alanine
(2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-9-decenoic Acid, is a stable antimicrobial peptide, that can be isolated from the venom of wild bee Lasioglossum laticeps.
The Uses of (R)-N-Fmoc-2-(7'-octenyl) alanine
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
Properties of (R)-N-Fmoc-2-(7'-octenyl) alanine
| Boiling point: | 588.3±45.0 °C(Predicted) |
| Density | 1.140 |
| storage temp. | -20°C |
| pka | 3.94±0.41(Predicted) |
| form | liquid |
| color | pale yellow viscous |
Safety information for (R)-N-Fmoc-2-(7'-octenyl) alanine
| Signal word | Warning |
| Pictogram(s) |
 Environment GHS09 |
| GHS Hazard Statements |
H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for (R)-N-Fmoc-2-(7'-octenyl) alanine
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