(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

Synonym(s):(R)-(+)-Glyceraldehyde acetonide;(R)-Isopropylideneglyceraldehyde;NSC 89869

CAS NO.：15186-48-8
Empirical Formula: C6H10O3
Molecular Weight: 130.14
MDL number: MFCD00269682
EINECS: 676-289-8
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:27:13

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde Structural

What is (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde?

Chemical properties

Colorless Transparent Liquid

The Uses of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a reactant involved in organic reactions including:• ;Henry condensation reactions1• ;Synthesis of highly functionalized chiral aziridines2• ;Olefination of aldehydes3• ;C-H oxidations4• ;Aldol-type condensations5• ;Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents6• ;Hosomi-Sakurai reactions7

The Uses of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde_x000D__x000D_Discontinued, Unstable (cas# 15186-48-8) is a compound useful in organic synthesis.

The Uses of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

Reactant involved in organic reactions including:

Henry condensation reactions
Synthesis of highly functionalized chiral aziridines
Olefination of aldehydes
C-H oxidations
Aldol-type condensations
Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents
Hosomi-Sakurai reactions

Properties of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

Boiling point:	139 °C (lit.)
alpha	53.8 º (c=2, CHCl3)
Density	1.045 g/mL at 25 °C (lit.)
refractive index	n20/D 1.454(lit.)
Flash point:	143 °F
storage temp.	-20°C
solubility	Difficult to mix.
form	Liquid
color	Colorless to Pale Yellow
optical activity	[α]22/D +53.8°, c = 2 in chloroform
CAS DataBase Reference	15186-48-8(CAS DataBase Reference)
NIST Chemistry Reference	Acetone D-glyceraldehyde(15186-48-8)

Safety information for (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H227:Flammable liquids H303:Acute toxicity,oral H333:Acute toxicity,inhalation H351:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P403+P235:Store in a well-ventilated place. Keep cool.