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HomeProduct name list(R)-2-PROPYLOCTANOIC ACID

(R)-2-PROPYLOCTANOIC ACID

(R)-2-PROPYLOCTANOIC ACID Structural

What is (R)-2-PROPYLOCTANOIC ACID?

Description

Arundic acid is an inhibitor of astrocyte activation. It reduces increases in brain glial fibrillary acid protein (GFAP) and S100β levels, markers of astrocyte activation, in a rat model of permanent focal ischemia induced by middle cerebral artery occlusion when administered at a dose of 10 mg/kg. Arundic acid (3 and 10 mg/kg) decreases the number of TUNEL-positive neurons, reduces infarct size, and improves motor performance in the rotarod test in the same model. It also reduces descent time and time to turn in a pole test, indicating reversal of motor deficits, in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 30 mg/kg.

Chemical properties

Clear Colorless Oil

The Uses of (R)-2-PROPYLOCTANOIC ACID

An astrocyte modulating agent, in acute ischemic stroke.

What are the applications of Application

R-(?)-Arundic Acid is an astrocyte modulating agent

Storage

Store at +4°C

Properties of (R)-2-PROPYLOCTANOIC ACID

Boiling point: 289℃
Density  0.908
Flash point: 154℃
storage temp.  Refrigerator
solubility  Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly)
form  Oil
pka 4.82±0.40(Predicted)
color  Clear Colorless to Clear Pale Yellow

Safety information for (R)-2-PROPYLOCTANOIC ACID

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-2-PROPYLOCTANOIC ACID

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