(R)-(+)-2-Chloropropionic acid
- CAS NO.：7474-05-7
- Empirical Formula: C3H5ClO2
- Molecular Weight: 108.52
- MDL number: MFCD00064204
- EINECS: 626-432-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:15
What is (R)-(+)-2-Chloropropionic acid?
Chemical properties
Colourless Oil
The Uses of (R)-(+)-2-Chloropropionic acid
(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:???????
- Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.???????
- (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.???????
- 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.
Properties of (R)-(+)-2-Chloropropionic acid
| Melting point: | -12°C |
| Boiling point: | 185-188 °C (lit.) |
| alpha | 14 º (neat) |
| Density | 1.258 g/mL at 20 °C (lit.) |
| refractive index | n |
| Flash point: | 140 °F |
| storage temp. | −20°C |
| solubility | soluble in Chloroform, Methanol |
| form | clear liquid |
| pka | 2.96±0.10(Predicted) |
| color | Colorless to Almost colorless |
| optical activity | [α]20/D +14°, neat |
| BRN | 1720258 |
| CAS DataBase Reference | 7474-05-7(CAS DataBase Reference) |
Safety information for (R)-(+)-2-Chloropropionic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(+)-2-Chloropropionic acid
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