R-1530
Synonym(s):5-(2-Chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine
- CAS NO.：882531-87-5
- Empirical Formula: C18H14ClFN4O
- Molecular Weight: 356.78
- MDL number: MFCD23704870
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is R-1530?
The Uses of R-1530
R 1530 is a multi-kinase inhibitor. It exhibits inhibitory activity against Chk2, KDR, FGFR, Aurora A kinase and Cdk2. It also binds VEGFR-2, FGFR1 and PDGFRβ. It displays antiproliferative activity in vitro and inhibits mitosis and angiogenesis.
Properties of R-1530
| Boiling point: | 550.9±50.0 °C(Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble20mg/mL, clear |
| pka | 17.23±0.40(Predicted) |
| form | powder |
| color | , white to yellow to light brown |
Safety information for R-1530
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for R-1530
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