(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

CAS NO.：82572-04-1
Empirical Formula: C12H14ClN
Molecular Weight: 207.69926
MDL number: MFCD07369798
EINECS: 617-358-4
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 04:13:26

What is (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride?

The Uses of (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.

Properties of (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

Melting point:	253-257 °C(lit.)
storage temp.	Sealed in dry,Room Temperature
optical activity	[α]/D 5.2±2°, c = 1 in methanol

Safety information for (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.