(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
- CAS NO.：82572-04-1
- Empirical Formula: C12H14ClN
- Molecular Weight: 207.69926
- MDL number: MFCD07369798
- EINECS: 617-358-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:27
What is (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride?
The Uses of (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
(R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is a pharmaceutical intermediate used in the preparation of cinacalcet hydrochloride, which treats secondary hyperparathyroidism due to chronic kidney disease. In addition, (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride is also used in analytical assays. Absolute configuration of primary amines determined using chiral (2-nitrophenyl)proline amides and 1H NMR.
Properties of (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
| Melting point: | 253-257 °C(lit.) |
| storage temp. | Sealed in dry,Room Temperature |
| optical activity | [α]/D 5.2±2°, c = 1 in methanol |
Safety information for (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(+)-1-(1-Naphthyl)ethylamine hydrochloride
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