QUINAPRILAT HYDRATE
Synonym(s):Quinaprilat
- CAS NO.：82768-85-2
- Empirical Formula: C23H26N2O5
- Molecular Weight: 410.46
- MDL number: MFCD08060097
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is QUINAPRILAT HYDRATE?
Chemical properties
Crystalline Solid
The Uses of QUINAPRILAT HYDRATE
A metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.
The Uses of QUINAPRILAT HYDRATE
Quinaprilat (Quinapril EP Impurity C) is a metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.
What are the applications of Application
Quinaprilat is a metabolite of Quinapril that acts as an ACE inhibitor
Definition
ChEBI: Quinaprilat is a dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a vasodilator agent. It is a dicarboxylic acid, a member of isoquinolines and a tertiary carboxamide.
Properties of QUINAPRILAT HYDRATE
| Melting point: | 166-1680C |
| alpha | D23 +20.9° (c = 1 in methanol) |
| Boiling point: | 674.5±55.0 °C(Predicted) |
| Density | 1.289±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | DMSO: ≥23mg/mL |
| form | powder |
| pka | 2.19±0.10(Predicted) |
| color | white to tan |
| optical activity | [α]/D +16 to +23 (C=1, MeOH) |
| CAS DataBase Reference | 82768-85-2 |
Safety information for QUINAPRILAT HYDRATE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H400:Hazardous to the aquatic environment, acute hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for QUINAPRILAT HYDRATE
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