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HomeProduct name listQUINAPRILAT HYDRATE

QUINAPRILAT HYDRATE

Synonym(s):Quinaprilat

QUINAPRILAT HYDRATE Structural

What is QUINAPRILAT HYDRATE?

Chemical properties

Crystalline Solid

The Uses of QUINAPRILAT HYDRATE

A metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.

The Uses of QUINAPRILAT HYDRATE

Quinaprilat (Quinapril EP Impurity C) is a metabolite of Quinapril, an angiotensin converting enzyme (ACE) inhibitor.

What are the applications of Application

Quinaprilat is a metabolite of Quinapril that acts as an ACE inhibitor

Definition

ChEBI: Quinaprilat is a dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a vasodilator agent. It is a dicarboxylic acid, a member of isoquinolines and a tertiary carboxamide.

Properties of QUINAPRILAT HYDRATE

Melting point: 166-1680C
alpha  D23 +20.9° (c = 1 in methanol)
Boiling point: 674.5±55.0 °C(Predicted)
Density  1.289±0.06 g/cm3(Predicted)
storage temp.  Refrigerator
solubility  DMSO: ≥23mg/mL
form  powder
pka 2.19±0.10(Predicted)
color  white to tan
optical activity [α]/D +16 to +23 (C=1, MeOH)
CAS DataBase Reference 82768-85-2

Safety information for QUINAPRILAT HYDRATE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for QUINAPRILAT HYDRATE

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