QPX7728-OH disodium
- CAS NO.：2170848-99-2
- Empirical Formula: C10H6BFNaO5-
- Molecular Weight: 258.95
- Update Date: 2026-07-16 07:06:08
What is QPX7728-OH disodium?
Biological Activity
QPX7728-OH disodium (compound 13) is a boronic acid β-lactamase inhibitor, exacted from WO2018005662A1, compound 13. QPX7728-OH disodium inhibits cleavage of Nitrocefin by purified class A, C and D enzymes, with Kis less than 0.1 μμ[1]. QPX7728-OH disodium potentiates Aztreonam and Tigemonam against strains expressing class A and class C enzymes, with MICs≤5 μg/mL. QPX7728-OH disodium potentiates Biapenem against strains expressing class A (KPC) or class D (OXA-48) carbapenemases, with MICs≤5 μg/mL[1].
References
[1]. Scott Hecker, et al. Boronic acid derivatives and therapeutic uses thereof. WO2018005662A1.
Properties of QPX7728-OH disodium
| storage temp. | Store at -20°C |
| form | Solid |
| color | Off-white to yellow |
Safety information for QPX7728-OH disodium
Computed Descriptors for QPX7728-OH disodium
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