PSI-7976
- CAS NO.：1190308-01-0
- Empirical Formula: C22H29FN3O9P
- Molecular Weight: 529.45
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 15:13:42
What is PSI-7976?
The Uses of PSI-7976
Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Properties of PSI-7976
| Melting point: | 76-82°C |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly) |
| form | Solid |
| pka | 9.39±0.10(Predicted) |
| color | White to Off-White |
Safety information for PSI-7976
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PSI-7976
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