PROTOVERATRINE A+B
- Empirical Formula: C82H126N2O29
- Molecular Weight: 1603.87
- MDL number: MFCD00135585
What is PROTOVERATRINE A+B?
Description
An alkaloid of Veratrum album, this base was first isolated by Salzberger and reexamined by Poethke. The above formula is due to Jacobs and Craig who also describe the melting point as varying with the rate of heating. It has [α]27D - 40° (pyridine) or - 9.1 ° (CHC13). The alkaloid dissolves in H2S04 giving a blue colour that changes to violet on heating. In HCl and H3P04, the colour is cherryred. The hydrochloride monohydrate forms small tablets, m.p. 234-6°C (dry, dec.); the hydro bromide trlhydrate melts at 230-2°C (dec.); the aurichloride, m.p. 199°C (dec.) and the picrate, m.p. 216-220°C (dec.). On alkaline hydrolysis the alkaloid yields protoverine, acetic, methylethylacetic and methylethylglycollic acids.
The Uses of PROTOVERATRINE A+B
Medicine to lower blood pressure.
Definition
A substance isolated from the Veratrum album plant. It is a mixture of two alka- loids, designated protoveratrine A and protovera- trine B.
brand name
Protalba (Marion Merrell Dow).
References
Salzberger., Arch. Pharm., 228,462 (1890)
Poethke., ibid, 275,571 (1937)
Jacobs, Craig.,!. Bioi. Chem., 143, 427 (1942)
Jacobs, Craig., ibid, 149,271 (1943)
Properties of PROTOVERATRINE A+B
| Melting point: | 275-283°C |
Safety information for PROTOVERATRINE A+B
Computed Descriptors for PROTOVERATRINE A+B
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
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