poly(L-lactide)

Synonym(s):PLA;PLLA;Polylactide;PLA, Poly(L-lactic acid);PLA, Poly(L-Lactic acid)

CAS NO.：33135-50-1
Empirical Formula: C6H8O4
Molecular Weight: 144.12532
MDL number: MFCD00166383
EINECS: 608-832-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-04 15:14:36

What is poly(L-lactide)?

Chemical properties

White powder

The Uses of poly(L-lactide)

Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.

The Uses of poly(L-lactide)

medical device

The Uses of poly(L-lactide)

PLLA can be used as a resorbable implant material for potential usage in biomedical applications. It can also be used in the formation of composite ceramic material for biological applications.

Definition

ChEBI: Lactide is a member of dioxanes.

General Description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Properties of poly(L-lactide)

Melting point:	153 °C
Density	1.27 g/cm3
storage temp.	2-8°C
optical activity	[α]22/D -153°, c = 0.5% in chloroform

Safety information for poly(L-lactide)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.