POKEWEED MITOGEN

The Uses of POKEWEED MITOGEN

Lectin from Phaseolus vulgaris (red kidney bean) has been used:

• it has been used as a positive control to treat cells
• to stimulate cell culture for the analysis of lymphocyte proliferation
• to stimulate T cells

The Uses of POKEWEED MITOGEN

Lectin from Phaseolus vulgaris (red kidney bean) is used in Lymphocyte Transformation Assay and culture medium.

The Uses of POKEWEED MITOGEN

Lectin from Phaseolus vulgaris (red kidney bean) has been used:

• for the stimulation of cluster of differentiation (CD4+) T cells
• for the activation of primary peripheral blood lymphocytes
• for the stimulation of peripheral blood mononuclear cells

General Description

Lectins are proteins of plant origin, which have the ability to bind to certain neuronal surface glycoproteins and glycolipids. This ability of theirs helps them to be used as neuroanatomical tracers, as they are taken and transported in a retrograde or anterograde fashion.

Biochem/physiol Actions

Lectin agglutinates cells and precipitates polysaccharides and glycoproteins. It has anti-cancer, anti-human immunodeficiency virus (anti-HIV) and anti-microbial infection properties. Lectin is associated with toxic allergens and hemagglutinins. Lectin inhibits mucosal atrophy, lowers type 2 diabetes and obesity, enhances nutrient absorption and regulates drug targeting.