PNU 37883 hydrochloride
- CAS NO.：57568-80-6
- Empirical Formula: C21H36ClN3O
- Molecular Weight: 381.98
- MDL number: MFCD03840615
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is PNU 37883 hydrochloride?
What are the applications of Application
U-37883A is a potent inhibitor of vascular smooth muscle KIR6 channels
Biological Activity
Novel antagonist selective for the vascular form of K ATP channel; inhibits K ATP currents in isolated mesenteric artery smooth muscle cells (K d = 65 nM) but not in cardiac or skeletal myocytes. In vivo, inhibits blood vessel relaxation and hypotension induced by pinacidil. Displays weak diuretic effects.
Storage
room temperature (desiccate)
Properties of PNU 37883 hydrochloride
| RTECS | QD9865500 |
| storage temp. | 2-8°C |
| solubility | DMSO: ~23 mg/mL |
| form | powder |
| color | white |
Safety information for PNU 37883 hydrochloride
Computed Descriptors for PNU 37883 hydrochloride
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