Plerixafor N-Oxide
- Molecular Weight: 0
What is Plerixafor N-Oxide?
The Uses of Plerixafor N-Oxide
Plerixafor N-Oxide is an impurity of Plerixafor (P580500), which is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin''s lymphoma (NHL) and multiple myeloma (MM). Selective CXCR4 antagonist.
Safety information for Plerixafor N-Oxide
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