Piperitone

Synonym(s):p-Menth-1-en-3-one;3-Carvomenthenone;6-Isopropyl-3-methyl-2-cyclohexen-1-one

CAS NO.：89-81-6
Empirical Formula: C10H16O
Molecular Weight: 152.23
MDL number: MFCD00045532
EINECS: 201-942-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:54:09

What is Piperitone?

The Uses of Piperitone

Piperitone is a monoterpene compound that has a fresh minty camphor-like odour, and naturally occurs in extracts of commercial oil of peppermint. Piperitone is also used as a starting material in the synthesis of Thymol (T413000), a phenolic compound that is used for its antibacterial properties.

Definition

ChEBI: A p-menthane monoterpenoid that is cyclohex-2-en-1-one substituted by a methyl group at position 3 and an isopropyl group at position 6.

Production Methods

Piperitone is produced:
by isolation from Japanese Mint oil (dextro-Piperitone),
by isolation from Eucalyptus dives oil (laevo-Piperitone),
by hydrogenation of Diosphenol,
by reduction of 5-Methyl-2-iso-propylanisole with Sodium in liquid Ammonia.
laevo-Piperitone can also be produced from laevo-beta-Pinene via l-Limonene, by hydrogenation to /-Carvomenthene, and via 4 further intermediate steps to Piperitone.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Properties of Piperitone

Melting point:	-29 °C
Boiling point:	233°C
Density	0,93 g/cm³
refractive index	-60 ° (C=4, benzene)
FEMA	2910 \| D-PIPERITONE
storage temp.	2-8°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Oil
color	Colourless to Pale Yellow
Odor	at 10.00 % in dipropylene glycol. herbal minty camphor medicinal
JECFA Number	435
Merck	7473
EPA Substance Registry System	Piperitone (89-81-6)

Safety information for Piperitone

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.