Pinacol vinylboronate

Synonym(s):2-Ethenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Vinyl-4,4,5,5-tetramethyl-1,3,2-dioxaoborolane;4,4,5,5-Tetramethyl-2-vinyl-1,3,2-dioxaborolane

Clear colorless to amber liquid

suzuki reaction

Reagent used for

Suzuki-Miyaura coupling reactions
Mizoroki-Heck reactions (cascade reaction)
Intramolecular Nozaki-Hiyama-Kishi reactions
Stereoselective Cu-catalyzed γ-selective and stereospecific coupling
Control of stereoselectivity and mechanistic portrait on intramolecular (4+1)-cycloaddition of dialkoxycarbenes
Regio- and stereoselective synthesis of trisubstituted alkenes via gold(I)-catalyzed hydrophosphoryloxylation of haloalkynes followed by Pd-catalyzed consecutive cross-coupling reactions
Asymmetric Birch reductive alkylation

Reagent used in Preparation of

Molecular tubes for lipid sensing
Enzymatic inhibitors, antibiotics, receptor analogs, and other biologically significant compounds (including total syntheses)

Boiling point:	52-54°C 24mm
Density	0.908 g/mL at 25 °C (lit.)
refractive index	n20/D 1.4300(lit.)
Flash point:	94 °F
storage temp.	-20°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Powder or Low Melting Solid
color	White to yellow
Sensitive	Air Sensitive
Stability:	Light Sensitive, Volatile
CAS DataBase Reference	75927-49-0(CAS DataBase Reference)

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H226:Flammable liquids H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.