Phthalimide-PEG3-C2-OTs
- CAS NO.：382162-12-1
- Empirical Formula: C23H27NO8S
- Molecular Weight: 477.53
- MDL number: MFCD29079274
- Update Date: 2025-04-17 18:22:24
What is Phthalimide-PEG3-C2-OTs?
Biological Activity
Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG3-C2-OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Stegmaier P, et al. Photoactive branched and linear surface architectures for functional and patterned immobilization of proteins and cells onto surfaces: a comparative study. Chemphyschem. 2009 Feb 2;10(2):357-69.
Properties of Phthalimide-PEG3-C2-OTs
| Boiling point: | 624.4±55.0 °C(Predicted) |
| Density | 1.300±0.06 g/cm3(Predicted) |
| pka | -2.26±0.20(Predicted) |
Safety information for Phthalimide-PEG3-C2-OTs
Computed Descriptors for Phthalimide-PEG3-C2-OTs
New Products
Sodium glycochenodeoxycholate, >98% Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Gabapentin EP Impurity A 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 1,3-Diphenylurea 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID N-METHYL INDAZOLE-3-CARBOXYLIC ACID Zinc Bis-glycinate 2-Hydroxy-5-nitroacetophenone 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylate 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2-HYDROXY BENZYL CYANIDE DIETHYL AMINOMALONATE HYDROCHLORIDE 5-BROMO-2CYANO PYRIDINE Boldenone Clarithromycin Ethinyl Estradiol StanozololYou may like
-
CIS BROMO BENZOATE 98%View Details
61397-56-6 -
90-01-7 2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
3-NITRO 2-METHYL BENZOIC ACID 98%View Details
1975-50-4 -
INDAZOLE-3-CARBOXYLIC ACID 4498-67-3 98%View Details
4498-67-3 -
221615-75-4 2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 98%View Details
221615-75-4 -
(6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE 98%View Details
0/2/39 -
2033-24-1 MELDRUMS ACID 98%View Details
2033-24-1 -
42831-50-5 98%View Details
42831-50-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.