Phenyl vinyl sulfone
- CAS NO.：5535-48-8
- Empirical Formula: C8H8O2S
- Molecular Weight: 168.21
- MDL number: MFCD00007554
- EINECS: 226-890-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-04 15:22:50
What is Phenyl vinyl sulfone?
Chemical properties
off-white or tan powder
The Uses of Phenyl vinyl sulfone
As common reagent, Phenyl vinyl sulfone is used in a variety of cycloaddition reactions to form cyclopropanes,1 cyclohexenes,2,3 and cyclooctadienes.
The Uses of Phenyl vinyl sulfone
Phenyl Vinyl Sulfone is a synthetic inhibitor of cysteine protease and has antihelminthic and antiprotozoal properties. Phenyl Vinyl Sulfone is also an inhibitor of transpeptidase SrtA required for cell wall protein anchoring and virulence in Staphylococcus aureus.
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 4976, 1983 DOI: 10.1021/jo00173a039
General Description
Phenyl vinyl sulfone, a synthetic inhibitor of cysteine protease, exhibits antihelminthic and antiprotozoal properties.
Properties of Phenyl vinyl sulfone
| Melting point: | 67-69 °C (lit.) |
| Boiling point: | 267.16°C (rough estimate) |
| Density | 1.2660 (rough estimate) |
| refractive index | 1.5090 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | It is soluble in most common organic solvents. |
| form | Solid |
| color | White |
| BRN | 1906894 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 5535-48-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, (ethenylsulfonyl)-(5535-48-8) |
Safety information for Phenyl vinyl sulfone
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Phenyl vinyl sulfone
| InChIKey | UJTPZISIAWDGFF-UHFFFAOYSA-N |
Phenyl vinyl sulfone manufacturer
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