Perindoprilat
Synonym(s):(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid;Perindoprilat
- CAS NO.：95153-31-4
- Empirical Formula: C17H28N2O5
- Molecular Weight: 340.41
- MDL number: MFCD00865777
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is Perindoprilat?
Chemical properties
White to Off-White Solid
The Uses of Perindoprilat
Perindoprilat is the active metabolite of perindopril, an inhibitor of angiotensin converting enzyme (ACE) that has efficacy against hypertension. Perindoprilat specifically and competitively inhibits ACE in vitro with IC50 values ranging between 1.5 and 3.2 nM. Elimination of perindoprilat is decreased in the elderly and in patients with heart or renal failure.[Cayman Chemical]
The Uses of Perindoprilat
An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.
The Uses of Perindoprilat
Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor and antihypertensive.
What are the applications of Application
Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor
Definition
ChEBI: Perindoprilat is a dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a drug metabolite. It is an organic heterobicyclic compound, a dipeptide, a dicarboxylic acid and a L-alanine derivative.
Properties of Perindoprilat
| Melting point: | 153-155°C |
| Boiling point: | 568.1±45.0 °C(Predicted) |
| Density | 1.222±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.27±0.20(Predicted) |
| color | White to Pale Beige |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 95153-31-4 |
Safety information for Perindoprilat
Computed Descriptors for Perindoprilat
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2-(2-aminoethyl) benzenesulfonamide Gemcitabine 3-benzoate impurity Dihydroxyphenylacetone Ornidazole EP impurity D Acetyl amino diol impurity Valsartan Benzyl Ester Impurity B N,N'-Dicyclohexylcarbodiimide 3-Bromo-2-Methyl-5-Nitropyridine 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 2-Amino-4-Methylpyridine 4-Aminopyridine 4-dimethylaminopyridineRelated products of tetrahydrofuran
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