Pentafluorobenzoyl chloride
Synonym(s):Pentafluorobenzoic acid chloride;Perfluorobenzoyl chloride
- CAS NO.:2251-50-5
- Empirical Formula: C7ClF5O
- Molecular Weight: 230.52
- MDL number: MFCD00000657
- EINECS: 218-842-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:10
What is Pentafluorobenzoyl chloride?
Description
Pentafluorobenzoyl chloride is the acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography. It has a role as a chromatographic reagent. It is an acyl chloride and a perfluorinated compound. It derives from a pentafluorobenzoic acid.
2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivatize dimethylamine(DMA) in study to develop a rapid and accurate GC–MS method for determination of DMA in human urine. 2,3,4,5,6-Pentafluorobenzoyl chloride was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.
Chemical properties
clear colorless to light yellow liquid
The Uses of Pentafluorobenzoyl chloride
Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.
The Uses of Pentafluorobenzoyl chloride
Pentafluorobenzoyl chloride can be used for the derivatization of a variety of analytes including biological amines. There is an extensive use for the derivatization of lipids.
The Uses of Pentafluorobenzoyl chloride
A reagent used for deriving primary amines. 2,3,4,5,6-Pentafluorobenzoyl chloride was used for derivatization of 5-androstenediol, testosterone, estradiol , dihydrotestosterone and estrone in a study to determine their serum levels. 2,3,4,5,6-Pentafluorobenzoyl chloride was used to derivative dimethylamine(DMA) in study to develop a rapid and accurate GC-MS method for determination of DMA in human urine. It was used in a study to detect the presence of Enterobacter cloacae in cultures of Leuconostoc mesenteroide by gas chromatography/mass spectrometry.
What are the applications of Application
2,3,4,5,6-Pentafluorobenzoyl chloride is a reagent used for deriving primary amines
Definition
ChEBI: The acid chloride of pentafluorobenzoic acid. It is a sensitive derivatising reagent for the analysis of amines, amides and phenols by electron capture gas chromatography.
Properties of Pentafluorobenzoyl chloride
| Boiling point: | 158-159 °C(lit.) |
| Density | 1.601 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | None |
| storage temp. | Store below +30°C. |
| solubility | soluble in Chloroform |
| form | Liquid |
| Specific Gravity | 1.601 |
| color | Clear colorless to light yellow |
| Water Solubility | decomposes |
| Sensitive | Lachrymatory |
| BRN | 2054397 |
| Stability: | Moisture Sensitive |
| CAS DataBase Reference | 2251-50-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Pentafluorobenzoyl chloride(2251-50-5) |
Safety information for Pentafluorobenzoyl chloride
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Pentafluorobenzoyl chloride
| InChIKey | MYHOHFDYWMPGJY-UHFFFAOYSA-N |
New Products
Pentadecanoic acid 3-Bromophenylacetic acid 3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 3′-Hydroxyacetophenone 5-fluoro-1,3-benzodioxole 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole N-(4-Bromophenyl)-2-chloroacetamide 6-Isopropylpicolinonitrile N-Methyl-3,5-dinitro-2-pyridinamine Phenyl-boronic acid-d5 10,11-Dihdyro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide-d4 5-(2,4-difluorophenyl)oxazolidin-2-oneRelated products of tetrahydrofuran








You may like
-
Pentafluorobenzoyl chloride 95% CAS 2251-50-5View Details
2251-50-5 -
Pentafluorobenzoyl Chloride CAS 2251-50-5View Details
2251-50-5 -
2,3,4,5,6-Pentafluorobenzoyl chloride CAS 2251-50-5View Details
2251-50-5 -
1503408-77-2 6-Chloro-3,4-dimethylpyridin-2-amine 97-99%View Details
1503408-77-2 -
665020-24-6 ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99%View Details
665020-24-6 -
1187989-89-4 97-99%View Details
1187989-89-4 -
Methyl 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylate 97-99%View Details
1872090-65-7 -
32659-49-7 97-99%View Details
32659-49-7

