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HomeProduct name listpanepoxydone

panepoxydone

panepoxydone Structural

What is panepoxydone?

Biochem/physiol Actions

Panepoxydone is a fungal metabolite that inhibits NF-κB transcription factor by preventing IκB phosphorylation, thus inhibiting the release of NF-κB from the IκB : NF-κB complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi.

Properties of panepoxydone

Boiling point: 437.9±45.0 °C(Predicted)
Density  1.338±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO: soluble10mg/mL
form  powder
pka 12.67±0.40(Predicted)

Safety information for panepoxydone

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for panepoxydone

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