P-TOLYLUREA
- CAS NO.:622-51-5
- Empirical Formula: C8H10N2O
- Molecular Weight: 150.18
- MDL number: MFCD00025433
- EINECS: 210-739-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-08-15 12:14:24
What is P-TOLYLUREA?
Chemical properties
beige crystalline powder
General Description
Colorless crystals.
Air & Water Reactions
Slightly soluble in hot water.
Reactivity Profile
P-TOLYLUREA is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: Slightly toxic. Hazardous decomposition products.
Purification Methods
Crystallise the urea from H2O (m 186o), EtOH/water (1:1) or aqueous AcOH (m 184o). [Beilstein 12 H 941, 12 I 425, 12 II 512, 12 III 2084, 12 IV 1923.]
Properties of P-TOLYLUREA
| Melting point: | 178-181 °C |
| Boiling point: | 255℃ |
| Density | 1.192 |
| refractive index | 1.6180 (estimate) |
| Flash point: | 108℃ |
| storage temp. | 2-8°C |
| form | powder to crystal |
| pka | 14.61±0.50(Predicted) |
| color | White to Almost white |
| Water Solubility | 3.07g/L(45 ºC) |
| BRN | 2208088 |
| CAS DataBase Reference | 622-51-5(CAS DataBase Reference) |
| EPA Substance Registry System | p-Tolylurea (622-51-5) |
Safety information for P-TOLYLUREA
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for P-TOLYLUREA
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran






![4-[(ANILINOCARBONYL)AMINO]BENZOIC ACID](https://img.chemicalbook.in/CAS/GIF/5467-09-4.gif)

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