P-AMINOPHENYLMERCURIC ACETATE
Synonym(s):p-Aminophenylmercuric Acetate - CAS 6283-24-5 - Calbiochem;4-(Acetoxymercurio)aniline;APMA
- CAS NO.:6283-24-5
- Empirical Formula: C8H9HgNO2
- Molecular Weight: 351.75
- MDL number: MFCD00007820
- EINECS: 228-497-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:27:12
What is P-AMINOPHENYLMERCURIC ACETATE?
Chemical properties
OFF-WHITE TO BEIGE CRYSTALLINE POWDER AND CHUNKS
The Uses of P-AMINOPHENYLMERCURIC ACETATE
4-Aminophenylmercuric Acetate used in combination with heparin is said to be effective in activating matrix metalloproteinase-2 (MMP-2) in peripheral blood of healthy humans, according to biological studies.
Biochem/physiol Actions
An organomercurial activator of matrix metalloproteinases.
Safety Profile
Poison by intravenous and intraperitoneal routes. See also MERCURY COMPOUNDS, ANILINE. When heated to decomposition it emits very toxic fumes of NO, and Hg.
Purification Methods
Recrystallise it from hot dilute AcOH and dry it in air. Highly TOXIC. [Mahapatra et al. J Indian Chem Soc 32 613 1955, Albert & Schneider Justus Liebigs Ann Chem 465 269 1928, Beilstein 16 III 1411, 16 IV 1754.]
Properties of P-AMINOPHENYLMERCURIC ACETATE
| Melting point: | 163-165 °C (lit.) |
| storage temp. | +15C to +30C |
| solubility | DMSO: 10 mg/mL, soluble |
| form | solid |
| color | Colorless prisms from (CHCl3) |
| BRN | 3664749 |
| CAS DataBase Reference | 6283-24-5(CAS DataBase Reference) |
| EPA Substance Registry System | Mercury, (acetato-.kappa.O)(4-aminophenyl)- (6283-24-5) |
Safety information for P-AMINOPHENYLMERCURIC ACETATE
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 ![]() Health Hazard GHS08 ![]() Environment GHS09 |
| GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. |
Computed Descriptors for P-AMINOPHENYLMERCURIC ACETATE
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