OTS514

CAS NO.：1338540-63-8
Empirical Formula: C21H20N2O2S
Molecular Weight: 364.46
MDL number: MFCD29924710
EINECS: 604-604-1
Update Date: 2026-03-13 23:13:44

What is OTS514?

The Uses of OTS514

OTS514 is a potent T-lymphokine-activated killer cell-originated protein kinase (TOPK) inhibitor. TOPK is involved with cancer cell proliferation and cancer stem cell maintenance. OTS514 also downregulates the oncogenic transcriptional factor, forkhead box protein M1 (FOXM1).

Properties of OTS514

Boiling point:	501.3±50.0 °C(Predicted)
Density	1.293±0.06 g/cm3(Predicted)
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.25 mg/ml
form	A crystalline solid
pka	9.35±0.20(Predicted)
color	Light yellow to yellow

Safety information for OTS514

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for OTS514

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