Omadacycline (hydrochloride)

CAS NO.：1196800-39-1
Empirical Formula: C29H41ClN4O7
Molecular Weight: 593.12
Update Date: 2026-03-12 18:10:29

What is Omadacycline (hydrochloride)?

Description

Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The primary effect of omadacycline is on bacterial protein synthesis, inhibiting protein synthesis with a potency greater than that of tetracycline. The binding site for omadacycline is similar to that for tetracycline.

Properties of Omadacycline (hydrochloride)

storage temp.	Store at -20°C
form	Solid
color	Brown to black
Water Solubility	Water : ≥ 50 mg/mL (84.30 mM)

Safety information for Omadacycline (hydrochloride)

Computed Descriptors for Omadacycline (hydrochloride)

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