Oleocanthal

CAS NO.：289030-99-5
Empirical Formula: C17H20O5
Molecular Weight: 304.34
MDL number: MFCD30543617
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:11:52

What is Oleocanthal?

Description

Oleocanthal, a compound found in extra-virgin olive oil, causes an irritation in the back of the throat similarly to ibuprofen. Both of these molecules block cyclooxygenase enzymes. G. K. Beauchamp and co-workers recenly found that they activate a specific protein,TRPA1, that resides primarily in the back of the throat. These findings may explain why olive oil, like ibuprofen, combats inflammation.

The Uses of Oleocanthal

Oleocanthal is a compound of olive oil with potential use as anti-inflammatory and chemotherapeutic agents.

Definition

ChEBI: A carboxylic ester that is the 2-(p-hydroxyphenyl)ethyl ester of (3S)-4-formyl-3-(2-oxoethyl)hex-4-enoic acid. Oleocanthal is found in olive oil but it is not clear whether the natural product is a mixture of E

Properties of Oleocanthal

alpha	D25 -0.78° (c = 0.9 in chloroform)
Boiling point:	500.1±50.0 °C(Predicted)
Density	1.165±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	9.91±0.15(Predicted)
form	Oil
color	Colourless to Yellow Thick
Stability:	Hygroscopic, Unstable in Solution

Safety information for Oleocanthal

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Oleocanthal

New Products

2-(2-aminoethyl) benzenesulfonamide Gemcitabine 3-benzoate impurity Dihydroxyphenylacetone Ornidazole EP impurity D Acetyl amino diol impurity Valsartan Benzyl Ester Impurity B N,N'-Dicyclohexylcarbodiimide 3-Bromo-2-Methyl-5-Nitropyridine 5-Bromo-3-Methyl-2-Pyridinecarboxylic acid 2-Amino-4-Methylpyridine 4-Aminopyridine 4-dimethylaminopyridine