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HomeProduct name list(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Synonym(s):Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium (II)

(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Structural

What is (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium?

The Uses of (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H2O2-induced apoptosis using primary rabbit lens epithelial cells.

Biochem/physiol Actions

CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.

Storage

Store at -20°C

Properties of (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

storage temp.  -20°C
solubility  H2O: soluble20mg/mL, clear
form  powder
color  light yellow to dark yellow
Water Solubility  Soluble to 100 mM in water

Safety information for (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

Computed Descriptors for (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium

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