o-Toluoyl chloride
Synonym(s):2-Methylbenzoyl chloride
- CAS NO.：933-88-0
- Empirical Formula: C8H7ClO
- Molecular Weight: 154.59
- MDL number: MFCD00000668
- EINECS: 213-273-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:56
What is o-Toluoyl chloride?
Chemical properties
clear pale yellow to yellow to faintly pink liquid
The Uses of o-Toluoyl chloride
O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.
General Description
Flash vacuum pyrolysis of o-toluoyl chloride at 780°C and 0.5 mmHg yields benzocyclobutenone.
Properties of o-Toluoyl chloride
| Melting point: | 159.5-160.9 °C(Solv: ligroine (8032-32-4); dichloromethane (75-09-2)) |
| Boiling point: | 88-90 °C/12 mmHg (lit.) |
| Density | 1.185 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 170 °F |
| storage temp. | Room Temperature, Under Inert Atmosphere |
| form | Liquid |
| color | Clear pale yellow to yellow to faintly pink |
| Specific Gravity | 1.185 |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 507933 |
| CAS DataBase Reference | 933-88-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoyl chloride, 2-methyl-(933-88-0) |
| EPA Substance Registry System | Benzoyl chloride, 2-methyl- (933-88-0) |
Safety information for o-Toluoyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for o-Toluoyl chloride
| InChIKey | GPZXFICWCMCQPF-UHFFFAOYSA-N |
New Products
Cyclopropane-1,1-dicarboxylic acid Cyclopentane-1,2-dione 2-Bromo-5-iodopyridine 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Amino-4-methoxyben-zeneacetic acid 3-Aminophenylacetic acid 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 3-Hydroxypropionitrile valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 4-Bromo Benzylcyanide 5-azidovalericacid 4-bromo-1H-pyrazole-3-carboxylic acid Isopropyl amine Hydrochloride tert-butyl 4-(6-(8-cyclopentyl-5-methyl-7-oxo-6-vinyl-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)pyridin-3-yl)piperazine-1-carboxylateRelated products of tetrahydrofuran
You may like
-
933-88-0 O-Toluoyl Chloride 99%View Details
933-88-0 -
o-Methyl benzoylchloride 99%View Details
933-88-0 -
o-Methyl benzoylchloride 933-88-0 98%View Details
933-88-0 -
o-Toluoyl Chloride CAS 933-88-0View Details
933-88-0 -
o-Toluoyl chloride CAS 933-88-0View Details
933-88-0 -
1392213-15-8 98+View Details
1392213-15-8 -
39773-47-2 (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 98+View Details
39773-47-2 -
1392213-15-8 98+View Details
1392213-15-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.