o-Phenetidine

Synonym(s):2-Ethoxyaniline;2-Ethoxyaniline, 2′-Aminophenetol;o-Phenetidine

CAS NO.：94-70-2
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00007689
EINECS: 202-356-4
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 01:22:15

What is o-Phenetidine?

Chemical properties

deep red liquid

The Uses of o-Phenetidine

manufacture of dyes.

Definition

ChEBI: o-Phenetidine is a substituted aniline and an aromatic ether. It is used in the manufacture of acetophenetidin.

Preparation

o-Phenetidine is produced from 2- ethoxynitrobenzene by reduction with iron or by catalytic hydrogenation in the presence of precious-metal catalysts or Raney nickel.

General Description

Reddish brown oily liquid.

Air & Water Reactions

o-Phenetidine is very sensitive to exposure to light and air. . Slightly soluble in water.

Reactivity Profile

o-Phenetidine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

o-Phenetidine is probably combustible.

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.

Properties of o-Phenetidine

Melting point:	-20 °C
Boiling point:	231-233 °C(lit.)
Density	1.051 g/mL at 25 °C(lit.)
vapor pressure	1 mm Hg ( 67 °C)
refractive index	n20/D 1.555(lit.)
Flash point:	177 °F
storage temp.	Store at +15°C to +25°C.
solubility	soluble in alcohol and ether.
form	Liquid
pka	4.43(at 28℃)
color	Deep red
Water Solubility	0.5-1.0 g/100 mL at 24.5 ºC
Merck	14,7227
BRN	637069
CAS DataBase Reference	94-70-2(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2-ethoxy-(94-70-2)
EPA Substance Registry System	o-Phenetidine (94-70-2)

Safety information for o-Phenetidine

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.