Nomegestrol
- CAS NO.：58691-88-6
- Empirical Formula: C21H28O3
- Molecular Weight: 328.45
- MDL number: MFCD00867856
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-21 17:10:26
What is Nomegestrol?
Description
Nomegestrol acetate is the 19-nor derivative of megestrol acetate, useful in the treatment of gynecological conditions associated with luteal deficiency.
Description
Nomegestrol is a derivative of 19-norprogesterone. It increases nuclear levels of the progesterone receptor in rat uterus when administered at a dose of 1 mg/animal.
Originator
Theramex (Monaco)
The Uses of Nomegestrol
A progestogen, derivatives of which are used in contraceptives and hormone therapies.
The Uses of Nomegestrol
Progetin used in implantable hormone replacement therapies.
Background
Nomegestrol is an ingredient in the EMA-authorised product Zoely.
What are the applications of Application
Nomegestrol is a progestogen, derivatives are used in contraceptives and hormone therapies
Definition
ChEBI: Nomegestrol is a corticosteroid hormone.
brand name
LUTENYL
General Description
Nomegestrol acetate, 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate,is being investigated as the progestin component of anew oral contraceptive, in combination with the estrogenestradiol. This new combination, NOMAC/E2, is in phaseIII trials and would be the first oral contraceptive to utilizeestradiol itself as the estrogenic component. Structurally,NOMAC is considered a nor-progesterone derivative thatlacks the C19 methyl group in megestrol acetate.
Metabolism
Not Available
Properties of Nomegestrol
| Boiling point: | 502.6±50.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform: soluble,DMSO: slightly soluble,Methanol: slightly soluble |
| pka | 12.99±0.60(Predicted) |
| form | A solid |
Safety information for Nomegestrol
Computed Descriptors for Nomegestrol
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