N,N,2-TRIMETHYLPROPIONAMIDE

Synonym(s):N,N,2-Trimethylpropionamide

CAS NO.：21678-37-5
Empirical Formula: C6H13NO
Molecular Weight: 115.17
MDL number: MFCD00075378
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-16 09:55:32

What is N,N,2-TRIMETHYLPROPIONAMIDE?

Chemical properties

CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID

The Uses of N,N,2-TRIMETHYLPROPIONAMIDE

1- chloro-N,N-2-trimethylpropenylamine readily prepared' from N,N-dimethylisobutyramide. Isoxazoles are prepared by deprotonation of N,N-dimethylisobutyramide.

The Uses of N,N,2-TRIMETHYLPROPIONAMIDE

N,N-Dimethylisobutyramide may be used in the preparation of 1-chloro-N,N,2-trimethylpropenylamine.

General Description

N,N-Dimethylisobutyramide is an N,N-disubstituted amide. It can be prepared by acylation of secondary amines with acyl chloride.

Properties of N,N,2-TRIMETHYLPROPIONAMIDE

Boiling point:	175-176 °C744 mm Hg(lit.)
Density	0.892 g/mL at 25 °C(lit.)
refractive index	n20/D 1.439(lit.)
Flash point:	158 °F
form	clear liquid
pka	-0.47±0.70(Predicted)
Specific Gravity	0.910
color	Colorless to Almost colorless
Water Solubility	Soluble in water.
BRN	1742178
CAS DataBase Reference	21678-37-5

Safety information for N,N,2-TRIMETHYLPROPIONAMIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.