N,N-Dimethylglycine hydrochloride

Synonym(s):N,N-Dimethylaminoacetic acid hydrochloride;N,N-Dimethylaminoacetic acid hydrochloride;N,N-Dimethylglycine hydrochloride

CAS NO.：2491-06-7
Empirical Formula: C4H10ClNO2
Molecular Weight: 139.58
MDL number: MFCD00012610
EINECS: 219-648-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-12 09:16:39

N,N-Dimethylglycine hydrochloride Structural

What is N,N-Dimethylglycine hydrochloride?

Chemical properties

white crystalline powder

The Uses of N,N-Dimethylglycine hydrochloride

N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. Used in the development of glycine-based ionic liquids and emulsifiers. Also it is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).

Flammability and Explosibility

Not classified

Biochem/physiol Actions

N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).

Properties of N,N-Dimethylglycine hydrochloride

Melting point:	189-194 °C(lit.)
Boiling point:	397.74℃[at 101 325 Pa]
Density	1.326[at 20℃]
vapor pressure	0Pa at 25℃
storage temp.	Store below +30°C.
solubility	DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
form	Crystalline Powder
color	White
Odor	Slight to none
Water Solubility	100 g/L (20 ºC)
Sensitive	Hygroscopic
Merck	14,3244
BRN	3910578
CAS DataBase Reference	2491-06-7(CAS DataBase Reference)
EPA Substance Registry System	Glycine, N,N-dimethyl-, hydrochloride (2491-06-7)

Safety information for N,N-Dimethylglycine hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.