N,N-DIETHYL-2-PHENYLACETAMIDE
- CAS NO.：2431-96-1
- Empirical Formula: C12H17NO
- Molecular Weight: 191.27
- MDL number: MFCD00192031
- EINECS: 219-400-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is N,N-DIETHYL-2-PHENYLACETAMIDE?
The Uses of N,N-DIETHYL-2-PHENYLACETAMIDE
Insect repellent.
Synthesis Reference(s)
The Journal of Organic Chemistry, 46, p. 1215, 1981 DOI: 10.1021/jo00319a037
Metabolic pathway
When rats are exposed to whole-body attack by diethylphenylacetamide (DEPA), DEPA enters the systemic circulation when it is inhaled, and crosses air ? lung and lung ? blood barriers to be biodegraded and excreted. DEPA is converted by dealkylation and hydrolysis to the two acetamides, ethylphenylacetamide (EPA) and phenylacetamide (PA), and to phenylacetic acid (PhAA) which are excreted and identified as urinary metabolites.
Properties of N,N-DIETHYL-2-PHENYLACETAMIDE
| Melting point: | 84-86 °C |
| Boiling point: | 169-171 °C18 mm Hg(lit.) |
| Density | 1.004 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly),Methanol (Slightly) |
| pka | -0.44±0.70(Predicted) |
| form | Oil |
| color | Clear Colorless |
Safety information for N,N-DIETHYL-2-PHENYLACETAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N,N-DIETHYL-2-PHENYLACETAMIDE
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