NIPECOTAMIDE
Synonym(s):3-Carbamoylpiperidine;3-Piperidinecarboxamide
- CAS NO.：4138-26-5
- Empirical Formula: C6H12N2O
- Molecular Weight: 128.17
- MDL number: MFCD00005993
- EINECS: 223-962-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:59
What is NIPECOTAMIDE?
Chemical properties
YELLOW CRYSTALLINE POWDER
The Uses of NIPECOTAMIDE
Nipecotamide, is a budiling blcok used in the sythnesis of various compounds, such as DPP-4 inhibitors, IKKβ inhibitors, piroimidazolidinone NPC1L1 inhibitors, and Anti-HIV agents.
The Uses of NIPECOTAMIDE
Reactant for synthesis of:• ;DPP-4 inhibitors1• ;IKKβ inhibitors2• ;Spiroimidazolidinone NPC1L1 inhibitors3• ;Sulfamides4• ;Phosphodiesterase 5 inhibtors5• ;Anti-HIV agents6
Definition
ChEBI: The amide resulting from the formal condensation of nipecotic acid with ammonia.
Properties of NIPECOTAMIDE
| Melting point: | 103-106 °C(lit.) |
| Boiling point: | 237.61°C (rough estimate) |
| Density | 1.0754 (rough estimate) |
| refractive index | 1.4880 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 16.50±0.20(Predicted) |
| form | Crystalline Powder |
| color | Yellow |
| CAS DataBase Reference | 4138-26-5(CAS DataBase Reference) |
Safety information for NIPECOTAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for NIPECOTAMIDE
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
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