NICKEL CHLORIDE, DIMETHOXYETHANE ADDUCT

Synonym(s):Dichloro(dimethoxyethane)nickel;NiCl₂ glyme

Nickel(II) chloride ethylene glycol dimethyl ether is commonly used as a catalyst for the synthesis of various organic compounds.

Nickel(II) chloride ethylene glycol dimethyl ether complex can be used:

As a catalyst for the borylation of racemic benzylic chloride to synthesize enantioenriched benzylic boronic esters.
As a promoter for the trifluoromethylation of alkyl iodides to synthesize broad range of alkyl-CF₃ compounds.
For the synthesis of nickel bis(benzimidazol-2-ylidene) pincer complexes which can be used for electrocatalytic reduction of CO₂to CO.
As a Lewis acid catalyst for C-acylation β-ketoesters through photoactivation by visible light.

Nickel(II) chloride ethylene glycol dimethyl ether complex is a metal catalyst

Melting point:	>300 °C
storage temp.	Inert atmosphere,Room Temperature
form	Powder
color	yellow
Relative polarity	0.231
Sensitive	moisture sensitive

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H261:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H350:Carcinogenicity H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P273:Avoid release to the environment. P231+P232:Handle under inert gas. Protect from moisture. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.