Neopentyl glycol diglycidyl ether

Synonym(s):1,3-Bis(2,3-epoxypropoxy)-2,2-dimethylpropane;2,2′-[(2,2-Dimethyl-1,3-propanediyl)bis(oxymethylene)]bis[oxirane]

CAS NO.：17557-23-2
Empirical Formula: C11H20O4
Molecular Weight: 216.27
MDL number: MFCD00040687
EINECS: 241-536-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:26:40

Neopentyl glycol diglycidyl ether Structural

What is Neopentyl glycol diglycidyl ether ?

Chemical properties

colourless liquid

The Uses of Neopentyl glycol diglycidyl ether

Neopentyl Glycol Diglycidyl Ether is used in preparation of aqueous Epoxy curing agents for orange peel-like leveling coatings.

The Uses of Neopentyl glycol diglycidyl ether

Thismay be used as a bifunctional reactive diluent for viscosity reduction of resins with minimum change in cured resin properties and to allow increased filler incorporation.

The Uses of Neopentyl glycol diglycidyl ether

NGDE can be used in the synthesis of epoxy polymers for the development of shape memory polymers. It can also be used in the photopolymerization of cationic polymers.

Production Methods

The ether is made by condensing neopentyl glycol with epichlorohydrin followed by dehydrochlorination with caustic.

General Description

Clear liquid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Neopentyl glycol diglycidyl ether is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Neopentyl glycol diglycidyl ether is combustible.

Carcinogenicity

A 2 year dermal carcinogenicity study of NPGDGE in C3H mice was conducted at dose levels of 0.94, 1.87, and 3.75 mg/mouse . Skin tumor incidences were 10/50, 6/50, and 0/50 at 3.75, 1.87, and 0.94 mg/ mouse; no tumors occurred in the 300 acetone-treated controls. Tumor potency was calculated to be 1/700th that of benzo[a]pyrene, which was tested concurrently.

Properties of Neopentyl glycol diglycidyl ether

Boiling point:	103-107 °C/1 mmHg (lit.)
Density	1.04 g/mL at 25 °C (lit.)
vapor density	>1 (vs air)
refractive index	n20/D 1.457(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	clear liquid
color	Colorless to Almost colorless
Water Solubility	0.5-1.0 g/100 mL at 20.5 ºC
Stability:	Stable. Incompatible with strong oxidizing agents, sulfuric acid, dichromates. Combustible.
CAS DataBase Reference	17557-23-2(CAS DataBase Reference)
EPA Substance Registry System	Neopentyl glycol diglycidyl ether (17557-23-2)

Safety information for Neopentyl glycol diglycidyl ether

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.