NEBULARINE
- CAS NO.：550-33-4
- Empirical Formula: C10H12N4O4
- Molecular Weight: 252.23
- MDL number: MFCD00022819
- EINECS: 208-981-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is NEBULARINE?
Description
This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).
Chemical properties
Crystalline Solid
The Uses of NEBULARINE
Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.
What are the applications of Application
Nebularine is a purine nucleoside
Definition
ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.
Storage
+4°C
Purification Methods
Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]
Properties of NEBULARINE
| Melting point: | 181-182°C |
| Boiling point: | 395.4°C (rough estimate) |
| alpha | D25 -48.6° (H2O) |
| Density | 1.3402 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Ethanol, Methanol (Slightly) |
| form | Solid |
| pka | 13.13±0.70(Predicted) |
| color | Pale Beige to Beige |
| Merck | 13,6461 |
| Stability: | Hygroscopic |
Safety information for NEBULARINE
Computed Descriptors for NEBULARINE
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (4-Bromophenyl)(3-methoxyphenyl)methanone 4,5,7-Trimethyl-2(1H)-quinolinone 4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 2,6-Piperidinedione, 3-hydroxy-1-[(4-methoxyphenyl)methyl]- NA Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
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