N-TERT-BUTYLACRYLAMIDE
Synonym(s):N -(1,1-Dimethylethyl)-2-propenamide;N -t -Butylacrylamide
- CAS NO.：107-58-4
- Empirical Formula: C7H13NO
- Molecular Weight: 127.18
- MDL number: MFCD00026271
- EINECS: 203-505-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is N-TERT-BUTYLACRYLAMIDE?
Chemical properties
white to off-white powder or chunks
The Uses of N-TERT-BUTYLACRYLAMIDE
N-tert-Butylacrylamide is used for study on abiotic anti-VEGF nanoparticle for anti-angiogenic cancer therapy (1,2).
The Uses of N-TERT-BUTYLACRYLAMIDE
nTBA is temperature sensitive monomers that can be potentially used in drug delivery systems, dewatering of proteins, and immobilization of cells. It can be used in the preparation of poly(nTBA) based copolymeric hydrogels for bovin serum albumin.
General Description
N-tert-Butylacrylamide (nTBA) belongs to the class of hydrophobic acrylamides which can be synthesized by Ritter reaction and optimized by using N-tert-butyl acetate and acetic acid.
Flammability and Explosibility
Non flammable
Properties of N-TERT-BUTYLACRYLAMIDE
| Melting point: | 126-129 °C (lit.) |
| Boiling point: | 235.98°C (rough estimate) |
| Density | 1.0083 (rough estimate) |
| vapor pressure | 0.385Pa at 25℃ |
| refractive index | 1.4830 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 3.8g/L in organic solvents at 20 ℃ |
| form | Powder or Chunks |
| pka | 15.11±0.46(Predicted) |
| color | White to off-white |
| Water Solubility | 1g/L at 30℃ |
| BRN | 1742331 |
| CAS DataBase Reference | 107-58-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Propenamide, N-(1,1-dimethylethyl)- (107-58-4) |
Safety information for N-TERT-BUTYLACRYLAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for N-TERT-BUTYLACRYLAMIDE
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