N-Methylbenzene-1,2-diamine
- CAS NO.：4760-34-3
- Empirical Formula: C7H10N2
- Molecular Weight: 122.17
- MDL number: MFCD00192314
- EINECS: 225-297-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:53
What is N-Methylbenzene-1,2-diamine?
The Uses of N-Methylbenzene-1,2-diamine
N-Methyl-1,2-phenylenediamine may be used in the following studies:
- One-pot synthesis of 1-methyl-2(hetero)arylbenzimidazoles.
- Preparation of 1-methyl-1H-benzimidazole-2(3H)-thione.
- Total synthesis of the angiotensin II receptor antagonist, telmisartan.
- Preparation of benzimidazoles from ketene dithioacetals.
What are the applications of Application
N-Methyl-1,2-phenylenediamine is a reagent used in the preparation of benzimidazoles
Synthesis Reference(s)
Synthetic Communications, 19, p. 1381, 1989 DOI: 10.1080/00397918908054547
General Description
N-Methyl-1,2-phenylenediamine is an ortho-diamine. In situ generated diazonium cations of N-methyl-1,2-phenylenediamine were used for the electrochemical modification of glassy carbon electrode.
Properties of N-Methylbenzene-1,2-diamine
| Melting point: | 22 °C (lit.) |
| Boiling point: | 123-124 °C/10 mmHg (lit.) |
| Density | 1.075 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Liquid |
| pka | 6.17±0.10(Predicted) |
| color | Clear yellow to red to dark brown |
| CAS DataBase Reference | 4760-34-3(CAS DataBase Reference) |
| EPA Substance Registry System | 1,2-Benzenediamine, N-methyl- (4760-34-3) |
Safety information for N-Methylbenzene-1,2-diamine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Methylbenzene-1,2-diamine
| InChIKey | RPKCLSMBVQLWIN-UHFFFAOYSA-N |
New Products
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