N-METHYL-O-TOLUIDINE
Synonym(s):N-(2-Methylphenyl)methylamine;N,o-Dimethylaniline;N,2-Dimethylaniline;N,2-Dimethylbenzenamine;N-Methyl-N-(o-tolyl)amine
- CAS NO.：611-21-2
- Empirical Formula: C8H11N
- Molecular Weight: 121.18
- MDL number: MFCD00025627
- EINECS: 210-260-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:43:54
What is N-METHYL-O-TOLUIDINE?
Chemical properties
Clear liquid, darkening on storage
The Uses of N-METHYL-O-TOLUIDINE
Reactant for:
- Palladium-catalyzed coupling reactions
- Palladium-catalyzed amination of bromoindazoles
Synthesis Reference(s)
Tetrahedron, 42, p. 4027, 1986 DOI: 10.1016/S0040-4020(01)87558-X
General Description
N-Methyl-o-toluidine can be synthesized by reacting o-toluidine and benzotriazole.
Properties of N-METHYL-O-TOLUIDINE
| Melting point: | -10.08°C (estimate) |
| Boiling point: | 207 °C |
| Density | 0.97 |
| refractive index | 1.562-1.565 |
| Flash point: | 79.4 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| Water Solubility | Practically insoluble in water |
| pka | 4.72±0.10(Predicted) |
| form | clear liquid |
| color | White to Yellow to Green |
| CAS DataBase Reference | 611-21-2(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenamine, N,2-dimethyl- (611-21-2) |
Safety information for N-METHYL-O-TOLUIDINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. |
Computed Descriptors for N-METHYL-O-TOLUIDINE
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