N-(HYDROXYMETHYL)ACETAMIDE
- CAS NO.：625-51-4
- Empirical Formula: C3H7NO2
- Molecular Weight: 89.09
- MDL number: MFCD00014417
- EINECS: 210-897-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:07
What is N-(HYDROXYMETHYL)ACETAMIDE?
Chemical properties
white to light yellow crystalline powder
The Uses of N-(HYDROXYMETHYL)ACETAMIDE
N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.
The Uses of N-(HYDROXYMETHYL)ACETAMIDE
Antiseptic, disinfectant especially for surgical instruments.
Purification Methods
Recrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.]
Properties of N-(HYDROXYMETHYL)ACETAMIDE
| Melting point: | 48-52 °C |
| Boiling point: | 165.17°C (rough estimate) |
| Density | 1.14 |
| refractive index | 1.4368 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly, Sonicated), DMSO (Slightly), Methanol (Slightly) |
| pka | 13.28±0.10(Predicted) |
| form | Crystalline |
| color | White to Off-White Low-Melting |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| Merck | 14,4242 |
| BRN | 506226 |
| CAS DataBase Reference | 625-51-4(CAS DataBase Reference) |
Safety information for N-(HYDROXYMETHYL)ACETAMIDE
Computed Descriptors for N-(HYDROXYMETHYL)ACETAMIDE
| InChIKey | HWJHZLJIIWOTGZ-UHFFFAOYSA-N |
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
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