N-(HYDROXYMETHYL)ACETAMIDE
- CAS NO.：625-51-4
- Empirical Formula: C3H7NO2
- Molecular Weight: 89.09
- MDL number: MFCD00014417
- EINECS: 210-897-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is N-(HYDROXYMETHYL)ACETAMIDE?
Chemical properties
white to light yellow crystalline powder
The Uses of N-(HYDROXYMETHYL)ACETAMIDE
N-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.
The Uses of N-(HYDROXYMETHYL)ACETAMIDE
Antiseptic, disinfectant especially for surgical instruments.
Purification Methods
Recrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.]
Properties of N-(HYDROXYMETHYL)ACETAMIDE
| Melting point: | 48-52 °C |
| Boiling point: | 165.17°C (rough estimate) |
| Density | 1.14 |
| refractive index | 1.4368 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly, Sonicated), DMSO (Slightly), Methanol (Slightly) |
| pka | 13.28±0.10(Predicted) |
| form | Crystalline |
| color | White to Off-White Low-Melting |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| Merck | 14,4242 |
| BRN | 506226 |
| CAS DataBase Reference | 625-51-4(CAS DataBase Reference) |
Safety information for N-(HYDROXYMETHYL)ACETAMIDE
Computed Descriptors for N-(HYDROXYMETHYL)ACETAMIDE
| InChIKey | HWJHZLJIIWOTGZ-UHFFFAOYSA-N |
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
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