N-DESMETHYL IMATINIB
- CAS NO.：1356565-46-2
- Empirical Formula: C42H47N9O2
- Molecular Weight: 709.88
- MDL number: MFCD07369291
- Update Date: 2025-03-27 06:45:46
What is N-DESMETHYL IMATINIB?
The Uses of N-DESMETHYL IMATINIB
N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
The Uses of N-DESMETHYL IMATINIB
Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde is an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
Properties of N-DESMETHYL IMATINIB
| Melting point: | 180 - 190°C |
| Density | 1.248±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.20±0.70(Predicted) |
| color | Off-White to Light Yellow |
Safety information for N-DESMETHYL IMATINIB
Computed Descriptors for N-DESMETHYL IMATINIB
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Cyclopropane-1,1-dicarboxylic acid Cyclopentane-1,2-dione 2-Bromo-5-iodopyridine 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Amino-4-methoxyben-zeneacetic acid 3-Aminophenylacetic acid 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 3-Hydroxypropionitrile valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 4-Bromo Benzylcyanide 5-azidovalericacid 4-bromo-1H-pyrazole-3-carboxylic acid Isopropyl amine Hydrochloride tert-butyl 4-(6-(8-cyclopentyl-5-methyl-7-oxo-6-vinyl-7,8-dihydropyrido[2,3-d]pyrimidin-2-ylamino)pyridin-3-yl)piperazine-1-carboxylateRelated products of tetrahydrofuran
![4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide](https://img.chemicalbook.in/CAS/GIF/404844-11-7.gif)
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