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HomeProduct name listN-Carbobenzyloxy-L-valine

N-Carbobenzyloxy-L-valine

Synonym(s):N-Cbz-L-Valine;Z-L-Valine;Z-Val-OH

  • CAS NO.:1149-26-4
  • Empirical Formula: C13H17NO4
  • Molecular Weight: 251.28
  • MDL number: MFCD00008922
  • EINECS: 214-562-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-04-29 17:45:46
N-Carbobenzyloxy-L-valine Structural

What is N-Carbobenzyloxy-L-valine?

Chemical properties

white to light yellow crystal powde

The Uses of N-Carbobenzyloxy-L-valine

Valaciclovir intermediate

The Uses of N-Carbobenzyloxy-L-valine

Imatinib intermediate

The Uses of N-Carbobenzyloxy-L-valine

N-Cbz-L-valine is an N-Cbz-protected form of L-Valine (V094205). L-Valine is an essential amino acid that is used as an ingredient in cosmetic formulations, pharmaceuticals, and animal feed products. L-valine is also important for growth and ammonia detoxification in humans.

Synthesis Reference(s)

Synthesis, p. 738, 1985 DOI: 10.1055/s-1985-31329

Properties of N-Carbobenzyloxy-L-valine

Melting point: 62-64 °C(lit.)
Boiling point: 394.43°C (rough estimate)
alpha  -4 º (c=2,acetic acid)
Density  0,926g/cm
refractive index  -4.3 ° (C=2, AcOH)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Acetic Acid, DMSO (Slightly), Ethanol (Slightly)
form  Crystalline Powder
pka 4.00±0.10(Predicted)
color  White to off-white
optical activity [α]20/D 4.2±0.5°, c = 2 in chloroform
BRN  2056617
InChI InChI=1S/C13H17NO4/c1-9(2)11(12(15)16)14-13(17)18-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3,(H,14,17)(H,15,16)/t11-/m0/s1
CAS DataBase Reference 1149-26-4(CAS DataBase Reference)

Safety information for N-Carbobenzyloxy-L-valine

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H334:Sensitisation, respiratory
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Computed Descriptors for N-Carbobenzyloxy-L-valine

InChIKey CANZBRDGRHNSGZ-NSHDSACASA-N
SMILES C(O)(=O)[C@H](C(C)C)NC(OCC1=CC=CC=C1)=O

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